PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie

BACKGROUND: In prion disease, the peripheral expression of PrP(C) is necessary for the transfer of infectivity to the central nervous system. The spleen is involved in neuroinvasion and neural dissemination in prion diseases but the nature of this involvement is not known. The present study undertoo...

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Detalles Bibliográficos
Autores principales: Sørby, Randi, Austbø, Lars, Press, Charles McL., Skretting, Grethe, Landsverk, Thor, Espenes, Arild
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731221/
https://www.ncbi.nlm.nih.gov/pubmed/19727393
http://dx.doi.org/10.1371/journal.pone.0006885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731221/
https://www.ncbi.nlm.nih.gov/pubmed/19727393
http://dx.doi.org/10.1371/journal.pone.0006885

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