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Systems-Level Modeling of Cancer-Fibroblast Interaction

Cancer cells interact with surrounding stromal fibroblasts during tumorigenesis, but the complex molecular rules that govern these interactions remain poorly understood thus hindering the development of therapeutic strategies to target cancer stroma. We have taken a mathematical approach to begin de...

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Detalles Bibliográficos
Autores principales: Wadlow, Raymond C., Wittner, Ben S., Finley, S. Aidan, Bergquist, Henry, Upadhyay, Rabi, Finn, Stephen, Loda, Massimo, Mahmood, Umar, Ramaswamy, Sridhar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731225/
https://www.ncbi.nlm.nih.gov/pubmed/19727395
http://dx.doi.org/10.1371/journal.pone.0006888