Cargando…

Systems-Level Modeling of Cancer-Fibroblast Interaction

Cancer cells interact with surrounding stromal fibroblasts during tumorigenesis, but the complex molecular rules that govern these interactions remain poorly understood thus hindering the development of therapeutic strategies to target cancer stroma. We have taken a mathematical approach to begin de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wadlow, Raymond C., Wittner, Ben S., Finley, S. Aidan, Bergquist, Henry, Upadhyay, Rabi, Finn, Stephen, Loda, Massimo, Mahmood, Umar, Ramaswamy, Sridhar
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731225/ https://www.ncbi.nlm.nih.gov/pubmed/19727395 http://dx.doi.org/10.1371/journal.pone.0006888

Ejemplares similares

AKT1(low) quiescent cancer cells in ductal carcinoma in situ of the breast
por: Kabraji, Sheheryar, et al.
Publicado: (2019)

AKT1(low) quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer
por: Kabraji, Sheheryar, et al.
Publicado: (2017)

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer
por: Gallenne, Tristan, et al.
Publicado: (2017)

Induction of Stable Drug Resistance in Human Breast Cancer Cells Using a Combinatorial Zinc Finger Transcription Factor Library
por: Lee, Jeongeun, et al.
Publicado: (2011)

Sex differences in medico-legal action against doctors: a systematic review and meta-analysis
por: Unwin, Emily, et al.
Publicado: (2015)

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1
por: Javaid, Sarah, et al.
Publicado: (2013)

The role of the ubiquitination–proteasome pathway in breast cancer: Use of mouse models for analyzing ubiquitination processes
por: Rossi, Sabrina, et al.
Publicado: (2003)

When fat goes down, prostate cancer is on the ropes
por: Zadra, Giorgia, et al.
Publicado: (2019)

Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer
por: Priolo, Carmen, et al.
Publicado: (2015)

Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution
por: Liu, Xiaoqiu, et al.
Publicado: (2017)

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity
por: Kim, So Young, et al.
Publicado: (2010)

Disciplined doctors: Does the sex of a doctor matter? A cross-sectional study examining the association between a doctor's sex and receiving sanctions against their medical registration
por: Unwin, Emily, et al.
Publicado: (2014)

Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis
por: Miyoshi, N, et al.
Publicado: (2015)

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity
por: McMullin, Ryan P, et al.
Publicado: (2014)

SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
por: Tajima, Ken, et al.
Publicado: (2015)

A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis
por: Zadra, Giorgia, et al.
Publicado: (2014)

A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis
por: Zadra, Giorgia, et al.
Publicado: (2014)

Parental Home Vision Testing of Children During Covid-19 Pandemic
por: Painter, Sally, et al.
Publicado: (2021)

Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
por: Mohr, Mary E., et al.
Publicado: (2023)

50.2 When Family-Based Treatment (FBT) at the Dinner Table Isn't Enough: FBT in Intermediate Levels of Care
por: Bergquist, Avanti
Publicado: (2022)

Using SBAR in psychiatry: findings from two london hospitals
por: Janaway, Benjamin, et al.
Publicado: (2021)

Pre-diagnostic circulating sex hormone levels and risk of prostate cancer by ERG tumour protein expression
por: Graff, Rebecca E, et al.
Publicado: (2016)

Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer
por: Choi, Stephen Y. C., et al.
Publicado: (2022)

The effect of human amniotic epithelial cells on urethral stricture fibroblasts
por: Gottipamula, Sanjay, et al.
Publicado: (2019)

Surgeons’ Interactions With and Attitudes Toward E-Patients: Questionnaire Study in Germany and Oman
por: Masters, Ken, et al.
Publicado: (2020)

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
por: Barbie, David A., et al.
Publicado: (2009)

Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients
por: Wittner, Lucia, et al.
Publicado: (2017)

Krüppel-like Factor 2 (KLF2) in Immune Cell Migration
por: Wittner, Jens, et al.
Publicado: (2021)

Krüppel-like factor 2: a central regulator of B cell differentiation and plasma cell homing
por: Wittner, Jens, et al.
Publicado: (2023)

Cadmium–Zinc Interaction in Mus musculus Fibroblasts
por: Priante, Ettore, et al.
Publicado: (2022)

Phase I study of the (177)Lu-DOTA(0)-Tyr(3)-Octreotate (lutathera) in combination with nivolumab in patients with neuroendocrine tumors of the lung
por: Kim, Chul, et al.
Publicado: (2020)

Inhibition of proliferation and migration of stricture fibroblasts by epithelial cell-conditioned media
por: Nath, Nilima, et al.
Publicado: (2015)

Effect of myocyte-fibroblast coupling on the onset of pathological dynamics in a model of ventricular tissue
por: Sridhar, S., et al.
Publicado: (2017)

HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts
por: Bozaykut, Perinur, et al.
Publicado: (2020)

DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions
por: Yu, Jingkai, et al.
Publicado: (2008)

Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets
por: Amzallag, Arnaud, et al.
Publicado: (2019)

Interaction between human lung fibroblasts and T-lymphocytes prevents activation of CD4(+ )cells
por: Vancheri, Carlo, et al.
Publicado: (2005)

Channelpedia: An Integrative and Interactive Database for Ion Channels
por: Ranjan, Rajnish, et al.
Publicado: (2011)

ULTRASTRUCTURE OF BACTERIZED AND AXENIC TROPHOZOITES OF ENTAMOEBA HISTOLYTICA WITH PARTICULAR REFERENCE TO HELICAL BODIES
por: Rosenbaum, Robert M., et al.
Publicado: (1970)

Mastering Hyper-V Deployment
por: Finn, Aidan
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_l29tao61tjqpd26gh9ajri956r