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Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

OBJECTIVE: The generation of mature cell types during pancreatic development depends on the expression of many regulatory and signaling proteins. In this study, we tested the hypothesis that the transcriptional regulator Islet-1 (Isl-1), whose expression is first detected in the mesenchyme and epith...

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Detalles Bibliográficos
Autores principales: Du, Aiping, Hunter, Chad S., Murray, Johanna, Noble, Daniel, Cai, Chen-Leng, Evans, Sylvia M., Stein, Roland, May, Catherine Lee
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731519/
https://www.ncbi.nlm.nih.gov/pubmed/19502415
http://dx.doi.org/10.2337/db08-0987