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Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas
OBJECTIVE: The generation of mature cell types during pancreatic development depends on the expression of many regulatory and signaling proteins. In this study, we tested the hypothesis that the transcriptional regulator Islet-1 (Isl-1), whose expression is first detected in the mesenchyme and epith...
Autores principales: | Du, Aiping, Hunter, Chad S., Murray, Johanna, Noble, Daniel, Cai, Chen-Leng, Evans, Sylvia M., Stein, Roland, May, Catherine Lee |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731519/ https://www.ncbi.nlm.nih.gov/pubmed/19502415 http://dx.doi.org/10.2337/db08-0987 |
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