Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

OBJECTIVE: We investigated the effects of 18 confirmed type 2 diabetes risk single nucleotide polymorphisms (SNPs) on insulin sensitivity, insulin secretion, and conversion of proinsulin to insulin. RESEARCH DESIGN AND METHODS: A total of 5,327 nondiabetic men (age 58 ± 7 years, BMI 27.0 ± 3.8 kg/m(...

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Detalles Bibliográficos
Autores principales: Stančáková, Alena, Kuulasmaa, Teemu, Paananen, Jussi, Jackson, Anne U., Bonnycastle, Lori L., Collins, Francis S., Boehnke, Michael, Kuusisto, Johanna, Laakso, Markku
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731523/
https://www.ncbi.nlm.nih.gov/pubmed/19502414
http://dx.doi.org/10.2337/db09-0117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731523/
https://www.ncbi.nlm.nih.gov/pubmed/19502414
http://dx.doi.org/10.2337/db09-0117

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