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ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan

OBJECTIVE: Apolipoprotein CIII (apoCIII) is an independent risk factor for cardiovascular disease, but the molecular mechanisms involved are poorly understood. We investigated potential proatherogenic properties of apoCIII-containing LDL from hypertriglyceridemic patients with type 2 diabetes. RESEA...

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Detalles Bibliográficos
Autores principales: Hiukka, Anne, Ståhlman, Marcus, Pettersson, Camilla, Levin, Malin, Adiels, Martin, Teneberg, Susanne, Leinonen, Eeva S., Hultén, Lillemor Mattsson, Wiklund, Olov, Orešič, Matej, Olofsson, Sven-Olof, Taskinen, Marja-Riitta, Ekroos, Kim, Borén, Jan
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731525/
https://www.ncbi.nlm.nih.gov/pubmed/19502413
http://dx.doi.org/10.2337/db09-0206