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Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured Podocytes

OBJECTIVE: Monocyte chemoattractant protein-1 (MCP-1), a chemokine binding to the CC chemokine receptor 2 (CCR2) and promoting monocyte infiltration, has been implicated in the pathogenesis of diabetic nephropathy. To assess the potential relevance of the MCP-1/CCR2 system in the pathogenesis of dia...

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Detalles Bibliográficos
Autores principales: Tarabra, Elena, Giunti, Sara, Barutta, Federica, Salvidio, Gennaro, Burt, Davina, Deferrari, Giacomo, Gambino, Roberto, Vergola, Daniela, Pinach, Silvia, Perin, Paolo Cavallo, Camussi, Giovanni, Gruden, Gabriella
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731530/
https://www.ncbi.nlm.nih.gov/pubmed/19587356
http://dx.doi.org/10.2337/db08-0895