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Photodynamic therapy inhibits p-glycoprotein mediated multidrug resistance via JNK activation in human hepatocellular carcinoma using the photosensitizer pheophorbide a

BACKGROUND: Multidrug resistance (MDR) is frequently observed after prolonged treatment in human hepatoma with conventional anti-tumor drugs, and photodynamic therapy (PDT) is a recently suggested alternative to overcome MDR. The therapeutic potential of PDT was evaluated in a multidrug resistance (...

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Detalles Bibliográficos
Autores principales: Tang, Patrick Ming-Kuen, Zhang, Dong-Mei, Xuan, Ngoc-Ha Bui, Tsui, Stephen Kwok-Wing, Waye, Mary Miu-Yee, Kong, Siu-Kai, Fong, Wing-Ping, Fung, Kwok-Pui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731730/
https://www.ncbi.nlm.nih.gov/pubmed/19646254
http://dx.doi.org/10.1186/1476-4598-8-56