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Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients

BACKGROUND: Germline mono-allelic promoter hypermethylation of the MLH1 or MSH2 gene in families with hereditary nonpolyposis colorectal cancer has recently been reported. The purpose of this study was to evaluate if germline promoter hypermethylation of the tumor suppressor gene CDH1 (E-cadherin) m...

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Detalles Bibliográficos
Autores principales: Yamada, Hidetaka, Shinmura, Kazuya, Goto, Masanori, Iwaizumi, Moriya, Konno, Hiroyuki, Kataoka, Hideki, Yamada, Masami, Ozawa, Takachika, Tsuneyoshi, Toshihiro, Tanioka, Fumihiko, Sugimura, Haruhiko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731731/
https://www.ncbi.nlm.nih.gov/pubmed/19671196
http://dx.doi.org/10.1186/1476-4598-8-63