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Improving detection of differentially expressed gene sets by applying cluster enrichment analysis to Gene Ontology

BACKGROUND: Gene set analysis based on Gene Ontology (GO) can be a promising method for the analysis of differential expression patterns. However, current studies that focus on individual GO terms have limited analytical power, because the complex structure of GO introduces strong dependencies among...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Gu, JianLei, Zhou, Yan, Du, LinFang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731756/
https://www.ncbi.nlm.nih.gov/pubmed/19653916
http://dx.doi.org/10.1186/1471-2105-10-240