Using Expression and Genotype to Predict Drug Response in Yeast

Personalized, or genomic, medicine entails tailoring pharmacological therapies according to individual genetic variation at genomic loci encoding proteins in drug-response pathways. It has been previously shown that steady-state mRNA expression can be used to predict the drug response (i.e., sensiti...

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Detalles Bibliográficos
Autores principales: Ruderfer, Douglas M., Roberts, David C., Schreiber, Stuart L., Perlstein, Ethan O., Kruglyak, Leonid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731853/
https://www.ncbi.nlm.nih.gov/pubmed/19730698
http://dx.doi.org/10.1371/journal.pone.0006907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731853/
https://www.ncbi.nlm.nih.gov/pubmed/19730698
http://dx.doi.org/10.1371/journal.pone.0006907

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