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DR*W201/P65 Tetramer Visualization of Epitope-Specific CD4 T-Cell during M. tuberculosis Infection and Its Resting Memory Pool after BCG Vaccination

BACKGROUND: In vivo kinetics and frequencies of epitope-specific CD4 T cells in lymphoid compartments during M. tuberculosis infection and their resting memory pool after BCG vaccination remain unknown. METHODOLOGY/FINDINGS: Macaque DR*W201 tetramer loaded with Ag85B peptide 65 was developed to dire...

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Detalles Bibliográficos
Autores principales: Wei, Huiyong, Wang, Richard, Yuan, Zhuqing, Chen, Crystal Y., Huang, Dan, Halliday, Lisa, Zhong, Weihua, Zeng, Gucheng, Shen, Yun, Shen, Ling, Wang, Yunqi, Chen, Zheng W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731856/
https://www.ncbi.nlm.nih.gov/pubmed/19730727
http://dx.doi.org/10.1371/journal.pone.0006905