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Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance

The ardA gene, found in many prokaryotes including important pathogenic species, allows associated mobile genetic elements to evade the ubiquitous Type I DNA restriction systems and thereby assist the spread of resistance genes in bacterial populations. As such, ardA contributes to a major healthcar...

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Detalles Bibliográficos
Autores principales: McMahon, Stephen A., Roberts, Gareth A., Johnson, Kenneth A., Cooper, Laurie P., Liu, Huanting, White, John H., Carter, Lester G., Sanghvi, Bansi, Oke, Muse, Walkinshaw, Malcolm D., Blakely, Garry W., Naismith, James H., Dryden, David T. F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731889/
https://www.ncbi.nlm.nih.gov/pubmed/19506028
http://dx.doi.org/10.1093/nar/gkp478