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Translation inhibition reveals interaction of 2′-deoxy and 2′-O-methyl molecular beacons with mRNA targets in living cells

Understanding the interaction between oligonucleotide probes and RNA targets in living cells is important for biological and clinical studies of gene expression in vivo. Here, we demonstrate that starvation of cells and translation inhibition by blocking the mTOR or PI-3 kinase pathway could signifi...

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Detalles Bibliográficos
Autores principales: Nitin, Nitin, Rhee, Won Jong, Bao, Gang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731902/
https://www.ncbi.nlm.nih.gov/pubmed/19528073
http://dx.doi.org/10.1093/nar/gkp517