Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA

U1-snRNA is an integral part of the U1 ribonucleoprotein pivotal for pre-mRNA splicing. Toll-like receptor (TLR) signaling has recently been associated with immunoregulatory capacities of U1-snRNA. Using lung A549 epithelial/carcinoma cells, we report for the first time on interferon regulatory fact...

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Detalles Bibliográficos
Autores principales: Sadik, Christian D., Bachmann, Malte, Pfeilschifter, Josef, Mühl, Heiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731906/
https://www.ncbi.nlm.nih.gov/pubmed/19541850
http://dx.doi.org/10.1093/nar/gkp525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731906/
https://www.ncbi.nlm.nih.gov/pubmed/19541850
http://dx.doi.org/10.1093/nar/gkp525

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