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Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity
The type II restriction endonucleases are indispensible tools for molecular biology. Although enzymes recognizing nearly 300 unique sequences are known, the ability to engineer enzymes to recognize any sequence of choice would be valuable. However, previous attempts to engineer new recognition speci...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731914/ https://www.ncbi.nlm.nih.gov/pubmed/19567736 http://dx.doi.org/10.1093/nar/gkp535 |