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Affinity Density: a novel genomic approach to the identification of transcription factor regulatory targets

Methods: A new method was developed for identifying novel transcription factor regulatory targets based on calculating Local Affinity Density. Techniques from the signal-processing field were used, in particular the Hann digital filter, to calculate the relative binding affinity of different regions...

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Detalles Bibliográficos
Autores principales: Hazelett, Dennis J., Lakeland, Daniel L., Weiss, Joseph B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732317/
https://www.ncbi.nlm.nih.gov/pubmed/19401399
http://dx.doi.org/10.1093/bioinformatics/btp282