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Coal dust alters β-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells

BACKGROUND: Many polycyclic aromatic hydrocarbons (PAHs) can cause DNA adducts and initiate carcinogenesis. Mixed exposures to coal dust (CD) and PAHs are common in occupational settings. In the CD and PAH-exposed lung, CD increases apoptosis and causes alveolar type II (AT-II) cell hyperplasia but...

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Detalles Bibliográficos
Autores principales: Ghanem, Mohamed M, Battelli, Lori A, Law, Brandon F, Castranova, Vincent, Kashon, Michael L, Nath, Joginder, Hubbs, Ann F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732588/
https://www.ncbi.nlm.nih.gov/pubmed/19650907
http://dx.doi.org/10.1186/1743-8977-6-21