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Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae

BACKGROUND: Natural products are an important source of drugs and other commercially interesting compounds, however their isolation and production is often difficult. Metabolic engineering, mainly in bacteria and yeast, has sought to circumvent some of the associated problems but also this approach...

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Detalles Bibliográficos
Autores principales: Naesby, Michael, Nielsen, Søren VS, Nielsen, Curt AF, Green, Trine, Tange, Thomas Ø, Simón, Ernesto, Knechtle, Philipp, Hansson, Anders, Schwab, Markus S, Titiz, Olca, Folly, Christophe, Archila, Roberto E, Maver, Milena, van Sint Fiet, Stephan, Boussemghoune, Thiamo, Janes, Michael, Kumar, A S Sathish, Sonkar, Shailendra P, Mitra, Partha P, Benjamin, V Ajai Kumar, Korrapati, Nimitha, Suman, Inala, Hansen, Esben H, Thybo, Tanja, Goldsmith, Neil, Sorensen, Alexandra Santana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732597/
https://www.ncbi.nlm.nih.gov/pubmed/19678954
http://dx.doi.org/10.1186/1475-2859-8-45