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Pretreatment with Darbepoetin Attenuates Renal Injury in a Rat Model of Cisplatin-Induced Nephrotoxicity

BACKGROUND/AIMS: Darbepoetin alfa (DPO) exhibits comparable renoprotective effects to erythropoietin (EPO) in several animal models of acute renal injury. We examined whether DPO also attenuated renal injury in a rat model of cisplatin nephrotoxicity. METHODS: Male Spague-Dawley rats were divided in...

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Detalles Bibliográficos
Autores principales: Choi, Dae Eun, Jeong, Jin Young, Lim, Beom Jin, Lee, Kang Wook, Shin, Young-Tai, Na, Ki-Ryang
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732784/
https://www.ncbi.nlm.nih.gov/pubmed/19721861
http://dx.doi.org/10.3904/kjim.2009.24.3.238