Pharmacodynamic/Pharmacogenomic Modeling of Insulin Resistance Genes in Rat Muscle After Methylprednisolone Treatment: Exploring Regulatory Signaling Cascades

Corticosteroids (CS) effects on insulin resistance related genes in rat skeletal muscle were studied. In our acute study, adrenalectomized (ADX) rats were given single doses of 50 mg/kg methylprednisolone (MPL) intravenously. In our chronic study, ADX rats were implanted with Alzet mini-pumps giving...

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Detalles Bibliográficos
Autores principales: Yao, Zhenling, Hoffman, Eric P., Ghimbovschi, Svetlana, DuBois, Debra C., Almon, Richard R., Jusko, William J.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733097/
https://www.ncbi.nlm.nih.gov/pubmed/19787081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733097/
https://www.ncbi.nlm.nih.gov/pubmed/19787081

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