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Intracellular Calcium Deficits in Drosophila Cholinergic Neurons Expressing Wild Type or FAD-Mutant Presenilin

Much of our current understanding about neurodegenerative diseases can be attributed to the study of inherited forms of these disorders. For example, mutations in the presenilin 1 and 2 genes have been linked to early onset familial forms of Alzheimer's disease (FAD). Using the Drosophila centr...

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Detalles Bibliográficos
Autores principales: Michno, Kinga, Knight, David, Campussano, Jorge M., van de Hoef, Diana, Boulianne, Gabrielle L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733141/
https://www.ncbi.nlm.nih.gov/pubmed/19730737
http://dx.doi.org/10.1371/journal.pone.0006904