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Expression of catalytic proteasome subunits in the gut of patients with Crohn’s disease

BACKGROUND AND PURPOSE: Activation of the transcription factor NF-κB by proteasomes and subsequent nuclear translocation of cytoplasmatic complexes play a crucial role in the intestinal inflammation. Proteasomes have a pivotal function in NF-κB activation by mediating degradation of inhibitory IκB p...

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Detalles Bibliográficos
Autores principales: Visekruna, Alexander, Slavova, Nadia, Dullat, Sonja, Gröne, Jörn, Kroesen, Anton-Josef, Ritz, Jörg-Peter, Buhr, Heinz-Johannes, Steinhoff, Ulrich
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733182/
https://www.ncbi.nlm.nih.gov/pubmed/19274467
http://dx.doi.org/10.1007/s00384-009-0679-1