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Expression of catalytic proteasome subunits in the gut of patients with Crohn’s disease
BACKGROUND AND PURPOSE: Activation of the transcription factor NF-κB by proteasomes and subsequent nuclear translocation of cytoplasmatic complexes play a crucial role in the intestinal inflammation. Proteasomes have a pivotal function in NF-κB activation by mediating degradation of inhibitory IκB p...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733182/ https://www.ncbi.nlm.nih.gov/pubmed/19274467 http://dx.doi.org/10.1007/s00384-009-0679-1 |