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Epithelial Cells Derived from Human Embryonic Stem Cells Display P16(INK4A) Senescence, Hypermotility, and Differentiation Properties Shared by Many P63(+) Somatic Cell Types

Human embryonic stem (hES) cells can generate cells expressing p63, K14, and involucrin, which have been proposed to be keratinocytes. Although these hES-derived, keratinocyte-like (hESderK) cells form epithelioid colonies when cultured in a fibroblast feeder system optimal for normal tissue-derived...

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Detalles Bibliográficos
Autores principales: Dabelsteen, Sally, Hercule, Paula, Barron, Patricia, Rice, Meghan, Dorsainville, Gregory, Rheinwald, James G
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733375/
https://www.ncbi.nlm.nih.gov/pubmed/19489101
http://dx.doi.org/10.1002/stem.64