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Epithelial Cells Derived from Human Embryonic Stem Cells Display P16(INK4A) Senescence, Hypermotility, and Differentiation Properties Shared by Many P63(+) Somatic Cell Types
Human embryonic stem (hES) cells can generate cells expressing p63, K14, and involucrin, which have been proposed to be keratinocytes. Although these hES-derived, keratinocyte-like (hESderK) cells form epithelioid colonies when cultured in a fibroblast feeder system optimal for normal tissue-derived...
Autores principales: | Dabelsteen, Sally, Hercule, Paula, Barron, Patricia, Rice, Meghan, Dorsainville, Gregory, Rheinwald, James G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733375/ https://www.ncbi.nlm.nih.gov/pubmed/19489101 http://dx.doi.org/10.1002/stem.64 |
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