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Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not understood. We have dissected the stages of invadopodium assembly and maturation and show that invadopodia use cortactin phosphorylation as a mast...

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Detalles Bibliográficos
Autores principales: Oser, Matthew, Yamaguchi, Hideki, Mader, Christopher C., Bravo-Cordero, J.J., Arias, Marianela, Chen, Xiaoming, DesMarais, Vera, van Rheenen, Jacco, Koleske, Anthony J., Condeelis, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733743/
https://www.ncbi.nlm.nih.gov/pubmed/19704022
http://dx.doi.org/10.1083/jcb.200812176