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The BCL-2–like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2– and EAT-3/Opa1–dependent mitochondrial fusion

The mammalian dynamin-related guanosine triphosphatases Mfn1,2 and Opa1 are required for mitochondrial fusion. However, how their activities are controlled and coordinated is largely unknown. We present data that implicate the BCL-2–like protein CED-9 in the control of mitochondrial fusion in Caenor...

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Detalles Bibliográficos
Autores principales: Rolland, Stéphane G., Lu, Yun, David, Charles N., Conradt, Barbara
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733758/
https://www.ncbi.nlm.nih.gov/pubmed/19704021
http://dx.doi.org/10.1083/jcb.200905070