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Conformational Analysis of DNA Repair Intermediates by Time-Resolved Fluorescence Spectroscopy

[Image: see text] DNA repair enzymes are essential for maintaining the integrity of the DNA sequence. Unfortunately, very little is known about how these enzymes recognize damaged regions along the helix. Structural analysis of cellular repair enzymes bound to DNA reveals that these enzymes are able...

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Detalles Bibliográficos
Autores principales: Lin, Su, Horning, David P., Szostak, Jack W., Chaput, John C.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733762/
https://www.ncbi.nlm.nih.gov/pubmed/19673467
http://dx.doi.org/10.1021/jp906746w