Cargando…

ZNF93 Increases Resistance to ET-743 (Trabectedin; Yondelis®) and PM00104 (Zalypsis®) in Human Cancer Cell Lines

BACKGROUND: ET-743 (trabectedin, Yondelis®) and PM00104 (Zalypsis®) are marine derived compounds that have antitumor activity. ET-743 and PM00104 exposure over sustained periods of treatment will result in the development of drug resistance, but the mechanisms which lead to resistance are not yet un...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Zhenfeng, Choy, Edwin, Harmon, David, Yang, Cao, Ryu, Keinosuke, Schwab, Joseph, Mankin, Henry, Hornicek, Francis J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734182/
https://www.ncbi.nlm.nih.gov/pubmed/19742314
http://dx.doi.org/10.1371/journal.pone.0006967