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The Ataxic Cacna1a-Mutant Mouse Rolling Nagoya: An Overview of Neuromorphological and Electrophysiological Findings
Homozygous rolling Nagoya natural mutant mice display a severe ataxic gait and frequently roll over to their side or back. The causative mutation resides in the Cacna1a gene, encoding the pore-forming α(1) subunit of Ca(v)2.1 type voltage-gated Ca(2+) channels. These channels are crucially involved...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734259/ https://www.ncbi.nlm.nih.gov/pubmed/19484318 http://dx.doi.org/10.1007/s12311-009-0117-5 |