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A Statistical Model to Identify Differentially Expressed Proteins in 2D PAGE Gels

Two dimensional polyacrylamide gel electrophoresis (2D PAGE) is used to identify differentially expressed proteins and may be applied to biomarker discovery. A limitation of this approach is the inability to detect a protein when its concentration falls below the limit of detection. Consequently, di...

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Detalles Bibliográficos
Autores principales: Wu, Steven H., Black, Michael A., North, Robyn A., Atkinson, Kelly R., Rodrigo, Allen G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734266/
https://www.ncbi.nlm.nih.gov/pubmed/19763172
http://dx.doi.org/10.1371/journal.pcbi.1000509