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A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6

Motivation: High-resolution copy-number (CN) analysis has in recent years gained much attention, not only for the purpose of identifying CN aberrations associated with a certain phenotype, but also for identifying CN polymorphisms. In order for such studies to be successful and cost effective, the s...

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Detalles Bibliográficos
Autores principales: Bengtsson, Henrik, Wirapati, Pratyaksha, Speed, Terence P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734319/
https://www.ncbi.nlm.nih.gov/pubmed/19535535
http://dx.doi.org/10.1093/bioinformatics/btp371