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LRP1 Regulates Architecture of the Vascular Wall by Controlling PDGFRβ-Dependent Phosphatidylinositol 3-Kinase Activation

BACKGROUND: Low density lipoprotein receptor-related protein 1 (LRP1) protects against atherosclerosis by regulating the activation of platelet-derived growth factor receptor β (PDGFRβ) in vascular smooth muscle cells (SMCs). Activated PDGFRβ undergoes tyrosine phosphorylation and subsequently inter...

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Detalles Bibliográficos
Autores principales:	Zhou, Li, Takayama, Yoshiharu, Boucher, Philippe, Tallquist, Michelle D., Herz, Joachim
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734324/ https://www.ncbi.nlm.nih.gov/pubmed/19742316 http://dx.doi.org/10.1371/journal.pone.0006922

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