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AP-2α Induces Epigenetic Silencing of Tumor Suppressive Genes and Microsatellite Instability in Head and Neck Squamous Cell Carcinoma

BACKGROUND: Activator protein 2 alpha (AP-2α) is involved in a variety of physiological processes. Increased AP-2α expression correlates with progression in various squamous cell carcinomas, and a recent publication found AP-2α to be overexpressed in ∼70% of Head and Neck Squamous Cell Carcinoma (HN...

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Detalles Bibliográficos
Autores principales: Bennett, Kristi L., Romigh, Todd, Eng, Charis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734430/
https://www.ncbi.nlm.nih.gov/pubmed/19742317
http://dx.doi.org/10.1371/journal.pone.0006931