Adenovector GAD65 gene delivery into the rat trigeminal ganglion produces orofacial analgesia

BACKGROUND: Our goal is to use gene therapy to alleviate pain by targeting glial cells. In an animal model of facial pain we tested the effect of transfecting the glutamic acid decarboxylase (GAD) gene into satellite glial cells (SGCs) of the trigeminal ganglion by using a serotype 5 adenovector wit...

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Detalles Bibliográficos
Autores principales: Vit, Jean-Philippe, Ohara, Peter T, Sundberg, Christopher, Rubi, Blanca, Maechler, Pierre, Liu, Chunyan, Puntel, Mariana, Lowenstein, Pedro, Castro, Maria, Jasmin, Luc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734545/
https://www.ncbi.nlm.nih.gov/pubmed/19656360
http://dx.doi.org/10.1186/1744-8069-5-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734545/
https://www.ncbi.nlm.nih.gov/pubmed/19656360
http://dx.doi.org/10.1186/1744-8069-5-42

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