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Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites

BACKGROUND: Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations. Population differentiation (F(ST)) can evidence environmental selecti...

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Detalles Bibliográficos
Autores principales: Mattei, Josiemer, Parnell, Laurence D, Lai, Chao-Qiang, Garcia-Bailo, Bibiana, Adiconis, Xian, Shen, Jian, Arnett, Donna, Demissie, Serkalem, Tucker, Katherine L, Ordovas, Jose M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734553/
https://www.ncbi.nlm.nih.gov/pubmed/19682384
http://dx.doi.org/10.1186/1471-2156-10-45