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Nucleologenesis and embryonic genome activation are defective in interspecies cloned embryos between bovine ooplasm and rhesus monkey somatic cells

BACKGROUND: Interspecies somatic cell nuclear transfer (iSCNT) has been proposed as a tool to address basic developmental questions and to improve the feasibility of cell therapy. However, the low efficiency of iSCNT embryonic development is a crucial problem when compared to in vitro fertilization...

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Detalles Bibliográficos
Autores principales: Song, Bong-Seok, Lee, Sang-Hee, Kim, Sun-Uk, Kim, Ji-Su, Park, Jung Sun, Kim, Cheol-Hee, Chang, Kyu-Tae, Han, Yong-Mahn, Lee, Kyung-Kwang, Lee, Dong-Seok, Koo, Deog-Bon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734572/
https://www.ncbi.nlm.nih.gov/pubmed/19635167
http://dx.doi.org/10.1186/1471-213X-9-44