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No evidence for an association between the -36A>C phospholamban gene polymorphism and a worse prognosis in heart failure

BACKGROUND: In Brazil, heart failure leads to approximately 25,000 deaths per year. Abnormal calcium handling is a hallmark of heart failure and changes in genes encoding for proteins involved in the re-uptake of calcium might harbor mutations leading to inherited cardiomyopathies. Phospholamban (PL...

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Detalles Bibliográficos
Autores principales: Santos, Diogo GB, Medeiros, Alessandra, Brum, Patrícia C, Mill, José G, Mansur, Alfredo J, Krieger, José E, Pereira, Alexandre C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734742/
https://www.ncbi.nlm.nih.gov/pubmed/19638213
http://dx.doi.org/10.1186/1471-2261-9-33