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Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences

BACKGROUND: Ovarian cancer ascites fluid (OCAF), contains malignant cells, is usually present in women with an advanced stage disease and currently has no effective therapy. Hence, we developed a new therapy strategy to target the expression of diphtheria toxin gene under the control of H19 regulato...

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Detalles Bibliográficos
Autores principales: Mizrahi, Aya, Czerniak, Abraham, Levy, Tally, Amiur, Smadar, Gallula, Jennifer, Matouk, Imad, Abu-lail, Rasha, Sorin, Vladimir, Birman, Tatiana, de Groot, Nathan, Hochberg, Abraham, Ohana, Patricia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734756/
https://www.ncbi.nlm.nih.gov/pubmed/19656414
http://dx.doi.org/10.1186/1479-5876-7-69