Intestinal Microbiota Regulate Xenobiotic Metabolism in the Liver

BACKGROUND: The liver is the central organ for xenobiotic metabolism (XM) and is regulated by nuclear receptors such as CAR and PXR, which control the metabolism of drugs. Here we report that gut microbiota influences liver gene expression and alters xenobiotic metabolism in animals exposed to barbi...

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Detalles Bibliográficos
Autores principales: Björkholm, Britta, Bok, Chek Mei, Lundin, Annelie, Rafter, Joseph, Hibberd, Martin Lloyd, Pettersson, Sven
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734986/
https://www.ncbi.nlm.nih.gov/pubmed/19742318
http://dx.doi.org/10.1371/journal.pone.0006958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734986/
https://www.ncbi.nlm.nih.gov/pubmed/19742318
http://dx.doi.org/10.1371/journal.pone.0006958

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