Cyclophosphamide Chemotherapy Sensitizes Tumor Cells to TRAIL-Dependent CD8 T Cell-Mediated Immune Attack Resulting in Suppression of Tumor Growth

BACKGROUND: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to generate anti-tumor immune responses in the con...

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Detalles Bibliográficos
Autores principales: van der Most, Robbert G., Currie, Andrew J., Cleaver, Amanda L., Salmons, Joanne, Nowak, Anna K., Mahendran, Sathish, Larma, Irma, Prosser, Amy, Robinson, Bruce W. S., Smyth, Mark J., Scalzo, Anthony A., Degli-Esposti, Mariapia A., Lake, Richard A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734989/
https://www.ncbi.nlm.nih.gov/pubmed/19746156
http://dx.doi.org/10.1371/journal.pone.0006982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734989/
https://www.ncbi.nlm.nih.gov/pubmed/19746156
http://dx.doi.org/10.1371/journal.pone.0006982

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