Thyroid cancer in a patient with a germline MSH2 mutation. Case report and review of the Lynch syndrome expanding tumour spectrum

Lynch syndrome (HNPCC) is a dominantly inherited disorder characterized by germline defects in DNA mismatch repair (MMR) genes and the development of a variety of cancers, predominantly colorectal and endometrial. We present a 44-year-old woman who was shown to carry the truncating MSH2 gene mutatio...

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Detalles Bibliográficos
Autores principales: Stulp, Rein P, Herkert, Johanna C, Karrenbeld, Arend, Mol, Bart, Vos, Yvonne J, Sijmons, Rolf H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735069/
https://www.ncbi.nlm.nih.gov/pubmed/19706203
http://dx.doi.org/10.1186/1897-4287-6-1-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735069/
https://www.ncbi.nlm.nih.gov/pubmed/19706203
http://dx.doi.org/10.1186/1897-4287-6-1-15

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