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k-link EST clustering: evaluating error introduced by chimeric sequences under different degrees of linkage
Motivation: The clustering of expressed sequence tags (ESTs) is a crucial step in many sequence analysis studies that require a high level of redundancy. Chimeric sequences, while uncommon, can make achieving the optimal EST clustering a challenge. Single-linkage algorithms are particularly vulnerab...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735666/ https://www.ncbi.nlm.nih.gov/pubmed/19570806 http://dx.doi.org/10.1093/bioinformatics/btp410 |