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k-link EST clustering: evaluating error introduced by chimeric sequences under different degrees of linkage

Motivation: The clustering of expressed sequence tags (ESTs) is a crucial step in many sequence analysis studies that require a high level of redundancy. Chimeric sequences, while uncommon, can make achieving the optimal EST clustering a challenge. Single-linkage algorithms are particularly vulnerab...

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Detalles Bibliográficos
Autores principales: Bragg, Lauren M., Stone, Glenn
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735666/
https://www.ncbi.nlm.nih.gov/pubmed/19570806
http://dx.doi.org/10.1093/bioinformatics/btp410