Linking the p53 tumor suppressor pathway to somatic cell reprogramming

Reprogramming somatic cells to induced pluripotent stem (iPS) cells has been accomplished by expressing pluripotency factors and oncogenes1–8, but the low frequency and tendency to induce malignant transformation9 compromise the clinical utility of this powerful approach. We address both issues by i...

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Detalles Bibliográficos
Autores principales: Kawamura, Teruhisa, Suzuki, Jotaro, Wang, Yunyuan V., Menendez, Sergio, Morera, Laura Batlle, Raya, Angel, Wahl, Geoffrey M., Belmonte, Juan Carlos Izpisúa
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735889/
https://www.ncbi.nlm.nih.gov/pubmed/19668186
http://dx.doi.org/10.1038/nature08311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735889/
https://www.ncbi.nlm.nih.gov/pubmed/19668186
http://dx.doi.org/10.1038/nature08311

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