Searching for Factors that Distinguish Disease-Prone and Disease-Resistant Prions via Sequence Analysis

The exact mechanisms of prion misfolding and factors that predispose an individual to prion diseases are largely unknown. Our approach to identifying candidate factors in-silico relies on contrasting the C-terminal domain of PrP(C) sequences from two groups of vertebrate species: those that have bee...

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Detalles Bibliográficos
Autores principales: Kedarisetti, Kanaka Durga, Dick, Scott, Kurgan, Lukasz
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735959/
https://www.ncbi.nlm.nih.gov/pubmed/19812771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735959/
https://www.ncbi.nlm.nih.gov/pubmed/19812771

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