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A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell–lymphatic endothelium interaction

Malignant transformation of epithelial cells is frequently associated with the alteration of glycosylation pathways. Tn is a common tumor-associated carbohydrate antigen present in 90% of human carcinomas and its expression correlates with metastatic potential and poor prognosis. Despite its relevan...

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Detalles Bibliográficos
Autores principales: Danussi, Carla, Coslovi, Anna, Campa, Cristiana, Mucignat, Maria T, Spessotto, Paola, Uggeri, Fulvio, Paoletti, Sergio, Colombatti, Alfonso
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736043/
https://www.ncbi.nlm.nih.gov/pubmed/19528665
http://dx.doi.org/10.1093/glycob/cwp085