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A tumor cord model for Doxorubicin delivery and dose optimization in solid tumors

BACKGROUND: Doxorubicin is a common anticancer agent used in the treatment of a number of neoplasms, with the lifetime dose limited due to the potential for cardiotoxocity. This has motivated efforts to develop optimal dosage regimes that maximize anti-tumor activity while minimizing cardiac toxicit...

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Detalles Bibliográficos
Autor principal: Eikenberry, Steffen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736154/
https://www.ncbi.nlm.nih.gov/pubmed/19664243
http://dx.doi.org/10.1186/1742-4682-6-16